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Facial lipoatrophy symptoms

Familial partial lipodystrophy HIV lipoatrophy Lipoatrophy due to HIV infection and treatment Lipodystrophy of face Lipodystrophy, congenital Lipodystrophy, facial Clinical [icd9data.com] Symptoms typically develop around puberty, after having normal adipose tissue in childhood. 0002155 Insulin resistance Body fails to respond to insulin. A person with lipoatrophy may exhibit one or more of the following symptoms: You lose fat under your skin, arms, and legs and make your veins appear high on the skin. You may develop sunken cheeks and temples due to loss of fat in the face You may experience pain and tiredness while walking due to loss of fat in the soles of your feet

What Is Facial Wasting? Facial wasting is one symptom of a syndrome called lipoatrophy, which describes the loss of the soft layer of fat that sits just beneath the skin (subcutaneous fat). When a.. Lipoatrophy of the face is an uncommon disease that involves a reduction in facial adipose tissue, causing ab-normal indentation and asymmetry of the face.2,3 People with facial lipoatrophy may experience low self-esteem, depression, and social isolation.2 Facial lipoatrophy can occur due to natural or pathologi Symptoms If loss of orbital fat has caused enophthalmos, patients may complain of dry eye symptoms. Facial lipoatrophy can be stigmatizing and has been associated with depression

Facial wasting is one of lipoatrophy's main symptoms, with the loss of facial fat being one of the most recognizable traits, in addition to fat loss in the legs, arms, and buttocks. The root cause of lipoatrophy is not known Lipodystrophy Symptoms Since the disease results from different metabolic disorders, the symptoms of the disease may vary. Listed below are the common clinical manifestations of the disease: Partial or generalized loss of subcutaneous fat Lipodystrophy is a problem with the way your body uses and stores fat. It changes the way you look and can cause serious complications. It's called acquired lipodystrophy when you aren't born with it Lipodystrophy may cause other symptoms and issues. Metabolic complications, including increased hunger due to low levels of leptin, the hormone that signals satiation to the body, are common. Other..

Facial Lipoatrophy Causes & Reasons - Symptom

Lipoatrophy - Pictures, Causes, What Is, Treatment, Symptom

Facial Wasting - TheBod

  1. Hope of Treatments Beyond Facial FillersThere is currently no cure for lipoatrophy. Even the so-called treatments, such as poly-L-lactic acid (Sculptra, New-Fill), Radiesse (calcium hydroxylapatite
  2. Facial Wasting in Washington D.C. Facial wasting is one symptom of a syndrome called lipoatrophy - or the loss of the soft layer of fat that sits just beneath the skin. Facial fat loss (lipoatrophy) causes hollowed out-sunken cheeks and temple areas of the face. The cheeks and other facial areas such as the temples become hollow, sunken or flat
  3. lipoatrophy (fat wasting or loss). HAART is associated with a number of side effects, including lipodystrophy syndrome, which is characterized by facial [lipoatrophy] hyperlipidemia, insulin resistance, and visceral fat redistribution. Of these symptoms, facial [lipoatrophy], whic
  4. A decade later, more pronounced facial lipoatrophy, new facial nodules, and posterior thigh pain developed. Laboratory testing showed leukopenia, elevated liver and muscle enzymes, hypertriglyceridemia, and a low level of high-density lipoprotein

Objective: We evaluated the long-term safety and efficacy of injectable poly-L-lactic acid (PLLA) for the correction of facial lipoatrophy. Methods: This was a randomized, open-label, comparative, single-centre study of injected PLLA in patients with HIV-related facial lipoatrophy. Thirty subjects were randomized to immediate or delayed PLLA treatments, administered as three sets of bilateral. Peripheral lipoatrophy is characterized by wasting of subcutaneous fat in the face and limbs. An adverse side effect associated with the earliest nucleoside reverse transcriptase inhibitors including zidovudine (AZT, Retrovir), stavudine (d4T, Zerit), and didanosine (ddI, Videx), lipoatrophy can result in sunken cheeks that reveal one's HIV status, causing feelings of stigma and psychological.

HTB. Lipoatrophy and facial wasting. 17 October 2000.Related: Conference reports, Side effects, Lipodystrophy and metabolic complications, Lipodystrophy Workshop (IWADRLH) 2 Toronto 2000. Simon Collins, HIV i-Base. Loss of subcutaneous fat from the face - principally from the zygomato-nasal-labial triangle, cheeks (orbicular, masseter muscles) and sub-zygomatic zone - is one of the most. Symptoms of lipoatrophy may include fever, pain, and fatigue. Lipoatrophy is an uncommon condition in which fat layers just underneath the skin start to disappear. The problem can occur in an isolated body part, such as the face or an arm, or cause widespread fat tissue loss Facial lipoatrophy associated with HIV infection was first described in 1998 as one of the symptoms of the generalized lipodystrophy, developing in patients receiving highly active antiretroviral therapy (HAART) . The pathogenesis of HIV-associated lipodystrophy is probably based on blockage of protein synthesis connected with lipid metabolism. Facial lipoatrophy is the loss of fat that supports the fullness, shape, and contour of the face. It is best known for its association with human immunodeficiency virus (HIV) infection, where the reported prevalence is up to 53%. However, lipoatrophy is also a common, natural part of the aging process and occurs in patients with certain cancers. was evaluated. A total of 84 HIV-infected patients receiving antiretroviral therapy and exhibiting dyslipidemia were interviewed in an urban hospital setting in Brazil in 2006 using a standardized questionnaire. Of the 84 patients exhibiting dyslipidemia, 40 patients also exhibited body changes, and of these, 25 had facial lipoatrophy. From a psychosocial perspective, patients presenting with.

Mild facial lipoatrophy may be barely noticeable to the person experiencing it and unnoticeable to others. If the lipoatrophy worsens, the outlines of the facial muscles can be seen and felt through the skin. Facial lipoatrophy can also result in fat loss around the nose and mouth (A) In frontal view, face and neck demonstrate facial lipoatrophy and circumferential neck lipohypertrophy. (B) In lateral view, lower face and neck demonstrate facial lipoatrophy and circumferential neck lipohypertrophy. [Source 34)] Other risk factors for lipodystrophy in people with HIV include: Age: Older people are at higher risk Facial Lipoatrophy: Appearances Are Not Deceiving. Lipodystrophy syndrome (LS) has been reported as visible markers that can identify HIV status. Changes in body shape are detrimental in terms of psychological welfare and may affect well-being and increase the stigma associated with HIV disease. In the current study, the psychosocial impact of.

Lipoatrophy was classified into 3 categories (adapted from James et al 16): mild (localized and mild facial lipoatrophy with an almost normal appearance), moderate (deeper and wider central cheek atrophy, with the facial muscles showing through), and severe (extends up toward the orbit; the facial skin lies directly on the muscles over a wide. Facial palsy (loss of muscle tone or droop on one or both sides of the face) Arthritis with severe joint pain and swelling, particularly the knees and other large joints. Intermittent pain in tendons, muscles, joints, and bones; Heart palpitations or an irregular heart beat (Lyme carditis) Episodes of dizziness or shortness of breat A physical examination revealed facial lipoatrophy, with loss of buccal fat pads and prominent zygomatic arches. She presented bilateral breast hypoplasia. The subcutaneous fat was preserved in other anatomic regions, particularly in the lower abdomen and thighs (Fig. 2 )

Picture of HIV Lipodystrophy Treatment RxList

Lipodystrophy-associated manifestations remain a challenge for persons infected with HIV disease and their care providers. Symptomatic HIV disease and side effects of medications are implicated in. Familial partial lipodystrophy type Köbberling is a rare subtype of early-onset familial partial lipodystrophy (FPL), characterized by fat loss in the lower limbs and abnormal fat increase in other areas. The symptoms are similar to those seen in familial partial lipodystrophy, Dunnigan type (the most common type of FPL). However, only arms and legs have fat loss, and there is a normal or.

Facial Lipoatrophy: Appearances Are Not Deceiving. Janac-journal of The Association of Nurses in Aids Care, 2009. Judy Mill. Ana Fernandes. Eduardo Donadi. Alcyone Machado. Ro Sanches. Judy Mill. Ana Fernandes Most cases of acquired facial lipoatrophy are part of the so-called Barraquer-Simons syndrome, or acquired partial lipodystrophy. This disease affects mostly women and typically begins in childhood.1 It was first reported by Mitchell and later by Barraquer in 1907 and Simons in 1911. Approximately 200 patients have been reported to date.2 This rare disorder is characterized by greatly.

Medicare Will Now Cover Facial Fillers for HIV Positive

  1. Fifty-one patients underwent facial filling. The self-perceived quality of life, facial image, and degree of depressive symptoms were measured by the Short-Form 36 and HIV/AIDS--Targeted quality of life questionnaires, by a visual analogue scale and by the Beck depression inventory, respectively, before and three months after treatment
  2. ent nasolabial folds, periorbital hollowing, and visible facial musculature. Also referred to as facial lipodystrophy syndrome (LDS), and facial wasting
  3. Symptoms may present themselves immediately upon sitting or standing, or increase gradually over a period of time. A common pattern with many CSF leak sufferers, particularly those with a small or intermittent spinal leak, is that symptoms may only become noticeable or severe later in the day
  4. Lipoatrophy — abnormal fat loss in the face, limbs, and buttocks. Fat loss in the face (facial wasting) is the most common presentation (Figure 1). Lipoatrophy is distinct from HIV-related wasting, which is a general loss of fat and lean muscle tissue. Lipohypertrophy — abnormal fat buildup in the abdomen, breasts (in both men and women.
  5. Lipodystrophy syndromes are a group of genetic or acquired disorders in which the body is unable to produce and maintain healthy fat tissue. The medical condition is characterized by abnormal or degenerative conditions of the body's adipose tissue.. (Lipo is Greek for fat, and dystrophy is Greek for abnormal or degenerative condition.) A more specific term, lipoatrophy, is used when.
  6. al fat
  7. Symptoms of lipohypertrophy. The main symptom of lipohypertrophy is the development of raised areas under the skin. These areas may have the following characteristics: small and hard or large and.

HIV-Associated Facial Lipoatrophy - EyeWik

Sculptra has been in use in Europe since 1999 for the treatment of lipoatrophy, as well as facial wrinkles and folds due to age. Since its approval by the FDA, these conditions can be treated with Sculptra here in the United States. Lipoatrophy. Lipoatrophy, also known as facial wasting, is the loss of fat in the face that gives the face a sunken, hollow look Lipoatrophy, also called lipodystrophy, is a condition which describes a loss of fat tissue in a localized area. Lipoatrophy, which usually occurs following frequent subcutaneous injections, is not a disease itself, but is a result of other conditions which lead to a loss of fat tissue in an area HIV-related lipodystrophy occurs when a person contracts HIV or starts ART. Lipodystrophy can mean both fat gain, or lipohypertrophy, and fat loss, also known as lipoatrophy. Parts of the body. The symptoms and severity of CGL can vary greatly from one person to another. The loss of adipose tissue that characterizes these disorders is sometimes referred to as lipoatrophy rather than lipodystrophy by some physicians. Individuals with severe facial lipodystrophy can undergo reconstructive facial surgery including fascial grafts. Facial lipoatrophy can lead to depression, the agency said in its decision, and that, in turn, can cause patients to stop or interrupt HAART, with adverse consequences for their health

Lipoatrophy due to insulin lispro during pump therapy has also been reported. • An 8-year-old girl with type 1 diabetes, whose HbA 1c concentrations had been 7.8-8.7% while she used two daily injections of human NPH and regular insulin with ultralente, and had only mild lipohypertrophy in the biceps area, was switched to CSII using lispro insulin because of increased HbA 1c and several. From the patient's point of view, facial atrophy is the most stigmatizing aspect of the syndrome and might badly influence treatment adherence, crucial for long term antiviral efficacy. We propose a topographical classification and grading of facial lipoatrophy, and describe local treatment with injectable hyaluronic acid in gel form

Lipodystrophy refers to abnormal changes in the way fat is distributed around the body, along with resulting metabolic complications. Loss of fat from an area is called lipoatrophy, while the accumulation of fat is termed lipohypertrophy.In people with lipodystrophy, either or both of these processes can occur We followed Keith as he visited Being Alive to treat the facial wasting he suffers due to HIV and early medications that were used to treat it. Credits: http..

Facial Volume Overview - Causes, Treatment Options, and

  1. Unlike many other symptoms of HIV infection or HIV-associated lipodystrophy syndrome, facial lipoatrophy may force patients to unmask their HIV status; more generally it suggests that an individual, who is otherwise healthy, is unwell [1]
  2. Patients were graded according to the lipoatrophy scale created by Dr. Julia James and her colleagues with the Division of Dermatology and Department of Ophthalmology of the University of British Columbia in Vancouver (1 = mild and localized lipoatrophy; 4 = severe lipoatrophy over a wide facial region including the orbits) (James, 2002)
  3. HIV-associated lipodystrophy is a syndrome that occurs in HIV-infected patients who are being treated with antiretroviral medications. Although the term HIV-associated lipodystrophy refers to abnormal central fat accumulation (lipohypertrophy) and localized loss of fat tissue (lipoatrophy), some patients have only lipohypertrophy, some have only lipoatrophy, and, less commonly, a subset of.
  4. Body shape changes - Includes fat loss (lipoatrophy) and fat gain (lipohypertrophy) or movement of fat from one area to another (redistribution) of the body. Metabolic complications - Includes increases in fats and sugars in the blood. People living with HIV can experience both body shape changes and metabolic complications
  5. Because of the greatly improved self-esteem and quality of life patients experience when the symptoms of facial lipoatrophy are reduced, many insurance companies have begun to provide coverage for Sculptra® treatments. By covering the cost of the procedure, these insurance companies help patients receive the treatment they need and reduce the.

In distinction to lipoatrophy (which describes local fat loss), lipodystrophy refers to both the accumulation of fat as well as the loss of fat in other areas. In HIV lipostrophy, the findings include subcutaneous fat loss in the malar and buccal fat pads, ie, facial lipoatrophy, as well as on the extremities Facial fat loss is among the major lipoatrophy symptoms. It may also result in losing fat in the buttocks, arms, and legs. Remedies. If you realize the fat loss your face is experiencing, please don't despair. Multiple steps can be taken to reverse aging symptoms and bring back your face's shape Lipoatrophy can cause a hollow appearance under the eyes, loss of lip definition, and sunken cheeks. Often referred to as a liquid facelift, Sculptra ® injections are used to treat these lipoatrophy symptoms, as well as deep facial folds and wrinkles, by increasing facial volume and restoring definition to the face to create a more.

Lipodystrophy - Pictures, Symptoms, Causes, Treatmen

Facial lipoatrophy (FL), the loss of subcutaneous facial fat, is not uncommon in individuals (particularly men) on antiretroviral therapy. FL is a distressing and stigmatising condition which affects self-esteem and may deter people from going onto antiretroviral treatment None of these had ever received treatment for their facial lipoatrophy. Of those patients receiving injections, some suffered from mild symptoms, some had severe symptoms; 27 of the original 30 HIV patients returned for the remainder of the study, which consisted of three sessions, two weeks apart Initially, the patient was treated with oral prednisone; later, steroid-sparing agents were used with modest improvement evidenced by resolution of his systemic symptoms and stabilization of the cutaneous findings. A decade later, more pronounced facial lipoatrophy, new facial nodules, and posterior thigh pain developed A congenital or acquired disorder characterized by abnormal loss or redistribution of the adipose tissue in the body. collection of rare conditions resulting from defective fat metabolism and characterized by atrophy of the subcutaneous fat; includes total, congenital or acquired, partial, abdominal infantile, and localized lipodystrophy

RADIESSE is indicated for subdermal implantation for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds and it is also intended for restoration and/or correction of the signs of facial fat loss (lipoatrophy) in people with human immunodeficiency virus. CONTRAINDICATION A case of HIV-associated facial lipoatrophy man immunodeficiency virus facial lipoatrophy. Long- treated with 1000-cs liquid injectable silicone. Dermatol Surg 2004; 30:548-51. term safety and efficacy will have to be proven with 10 Silicone granuloma is a recognized complication of ruptured silicone breast implants. Silicone granulomas manifest clinically as recurrent cellulitis-like reactions with pain, induration, nodules, ulceration, and local lymphadenopathy (enlarged lymph nodes) 1). Systemic complications have also been reported, including acute pneumonitis. Search for: Rare Disease Profiles; 5 Facts; Rare IQ; Rare Mystery; Facial wasting or facial lipoatrophy is the loss of subcutaneous fat from the face and is associated with medication for treatment of HIV infection. The risk of facial wasting has been lessened because of advances in antiretroviral therapy, but it still occurs

Physical symptoms: As explained earlier, the exact location of unintentional loss or gain of fat tissues varies greatly on an individual basis as well as the subtype of lipodystrophy that the patients are diagnosed with. Most patients who do experience fat loss—also called lipoatrophy—in areas like the face (e.g. cheeks and temples. Facial Lipoatrophy can negatively affect a number of different areas of a person's life, including: self-confidence, desire to participate in social activities, sex drive, emotional well-being, willingness or ability to adhere to treatment, commitment to staying on treatment Facial Lipoatrophy Panel was united by the recognition that the community of physicians treating facial lipoatrophy lack a shared vocabulary with which to discuss the full range of presentations, diagnoses, and treatments for the condition. The absence of a com-mon panspecialty language could hinder the exchange of informa-tion, ideas, and.

Acquired Lipodystrophy: Causes, Symptoms, Treatment

Lipoatrophy. Lipoatrophy, also known as facial wasting, is the loss of fat in the face that gives the face a sunken, hollow look. It is a condition suffered primarily by patients with HIV and AIDS. Sculptra was first approved by the FDA in 2004 for use on HIV and AIDS sufferers of lipoatrophy What are the symptoms of lipodystrophy? There are two main signs of lipodystrophy: fat loss and fat buildup. Men in particular tend to lose fat, and this is called lipoatrophy Lipodystrophy syndromes: New treatment, newer questions. Sept. 01, 2015. Lipodystrophies are a heterogeneous group of rare acquired and inherited disorders characterized by selective loss of adipose tissue. Vinaya Simha, MBBS, M.D., an endocrinology consultant at Mayo Clinic's campus in Rochester, Minnesota, says: While the first reported case.

Lipodystrophy: Pictures, definition, and cause

Fabulous Face is your destination for learning more about treatments for HIV Facial Wasting, choosing the right treatments and finding the perfect doctor 772-492-8105 Hom Lipoatrophy. When a loss of subcutaneous fat affects the face, it results in sunken cheeks and facial folds and indentations. The most common cause is associated with HIV (human immunodeficiency.

Progressive facial asymmetry may lead to serious deformations.Facial lipoatrophy associated with HIV infection was first described in 1998 as one of the symptoms of the generalized lipodystrophy, developing in patients receiving highly active antiretroviral therapy (HAART) [8] What are the Symptoms of Facial Lipoatrophy? Lipoatrophy can occur in the arms, legs, buttocks or waist but is, obviously, most noticeable in the face. Sunken cheeks are one of the most apparent indications, in severe cases even allowing the facial muscles to be visible and felt through the skin

Acquired Lipodystrophy - NORD (National Organization for

immunodeficiency viruseassociated facial lipoatro-phy, and was recently reported in a case of corticosteroid-induced lipoatrophy.12 Maximal improvement of the lipoatrophy was noted in 3 to 5 months.12 Our patient was followed over a 9-month period. The alternative treatments mentioned above are expensive and inconvenient, potentially prohibitin Facial lipoatrophy is one of the most difficult complication in the patients with lupus profundus. In this paper, we present a case of a 55-year-old woman affected by lupus profundus, with a grade V lipoatrophy, treated with lipofilling technique. No complications were observed and results at 12 months were stable, natural, and symmetric Facial lipoatrophy, or facial wasting, is one of the most visible symptoms of many HIV antiretroviral treatments. We have friends who cite facial wasting as among the worst side effects of.

Familial Partial Lipodystrophy (FPLD): Symptoms, Diagnosis

It became a common manifestation in the 1980's and persisted until the medications that caused the condition, known as facial lipoatrophy, were changed or abandoned for better treatment. Today, facial lipoatrophy is almost exclusively limited to long-term HIV survivors who used medications like d4t and ddi more than twenty years ago Lipodystrophy refers to the changes in body fat that can affect some people with HIV. Lipodystrophy can include buildup of body fat, loss of body fat, or both. Lipodystrophy may be due to HIV infection or medicines used to treat HIV. Newer HIV medicines are less likely to cause lipodystrophy than HIV medicines developed in the past HIV facial lipoatrophy who underwent autologous fat transplant with the Coleman method. 17 The technique was deemed reliable, and photographs at 6 months showed the durability of the fat graft. However, the authors noted that the majority of patients with HIV facial lipoatrophy lack adequate subcutaneous donor fat reserves, so many ar HIV Lipoatrophy Treatment A Face to Remember LipoatrophyHIV.com is a site dedicated to the education, treatment and information on the premier doctor for HIV Lipoatrophy

Acquired Lipodystrophy: Causes, Symptoms, TreatmentsFacial Wasting

Lipodystrophy : Facts, types, causes, symptoms

HIV-associated facial lipoatrophy. In that Section, facial lipoatrophy is defined and its impact on the lives of HIV patients is described. In the subsequent section, clinical trials of HIV-associated facial lipoatrophy treatments using poly-l-lactic acid and polyalkylimide gel are reviewed. 2.1 Overview of HIV-associated facial lipoatrophy Dermal fillers may help. Over time, age-related bone loss in the face can lead to retraction of the jawline, descent of the nose, and loss of high cheekbones. The facial muscles also decrease in volume and elasticity, and deflation and movement of facial fat further accentuates the signs of aging. Finally, the skin stretches and loses.

Lipodystrophy and HIV: Symptoms, Causes, Treatment

This page includes the following topics and synonyms: Lipodystrophy, Lipoatrophy, Peripheral Fat Wasting, Crix Belly, Protease Paunch, Buffalo Humps, Second Chins, Atrophic Facial Cheeks Koshy CE, Evans J. Facial contour reconstruction in localised lipodystrophy using free radial forearm adipofascial flaps. Br J Plast Surg. 1998 Oct. 51(7):499-502. . Peters MS, Winkelmann RK. Localized lipoatrophy (atrophic connective tissue disease panniculitis). Arch Dermatol. 1980 Dec. 116(12):1363-8. . Peters MS, Winkelmann RK Sculptra® is an injectable product that restores and corrects the signs of facial fat loss by replacing lost volume. Sculptra® provides an increase in skin thickness, helping to create a more natural facial appearance in those with facial lipoatrophy Commonly used options for HIV-related facial lipoatrophy (2) Table provided by PoWeR (Program for Wellness Restoration) and www.facialwasting.org. Source: Comparison of Poly-L-lactic Acid and Calcium Hydroxylapatite for Treating Human Immunodeficiency Virus-Associated Facial Lipoatrophy; Cosmetic Dermatology, May 2007, Vol 20 No. 5 PRODUCT TYPE.

Progressive hemifacial atrophy: Case reportPicture of the face and neck of the patient taken at thAcne Cosmetica | Dermgroup NYC

Decision Memo for Dermal injections for the treatment of

polylactic acid (PLA) for the treatment of facial lipoatrophy in HIV-infected adults. Methods A randomized, blinded, multicentre, noninferiority 96-week study was carried out. Patients with facial lipoatrophy were randomly assigned to receive intradermal injections with PH or PLA, and were blinded to the filler That's because many signs and symptoms of thyroid disease develop on the skin, hair, and nails. The thyroid gland. The thyroid is a butterfly-shaped gland in your neck that produces hormones, which play a key role in regulating your heartbeat, breathing, and many other functions About 13%-38% of HAART-treated patients suffer from facial lipoatrophy, leading some to discontinue their medications, according to the decision. Two fillers, Radiesse (calcium hydroxylapatite) and Sculptra (poly-L-lactic acid), are approved by the Food and Drug Administration to correct facial fat loss in people with HIV Sclerosing mesenteritis can cause abdominal pain, vomiting, bloating, diarrhea and fever. But some people experience no signs and symptoms and may never need treatment. In rare cases, scar tissue formed by sclerosing mesenteritis can block food from moving through your digestive tract. In this case, you may need surgery Facial lipoatrophy is a condition that results in loss of fat in the cheeks, temples and eye sockets. The sunken cheeks, hollow eyes, indentations and wrinkling may make a person appear exhausted and unhealthy, said Dr. Sharon Levy, senior director of Scientific & Medical Affairs for Dermik Laboratories

Radiesse Dermal Filler Volume Replacement | Willo MediSpa

Dermal fillers can be used in different face parts like cheeks, mouth, eye, jawline, and lips. They are helpful for those who have early symptoms of aging, or as an enhanced part of improving. Facial lipoatrophy can occur due to natural or pathological processes. 3 Natural or physiological lipoatrophy refers to the loss of facial fat due to senescence. 2 This type of adipose tissue loss generally starts at the age of 20 to 30 years and progresses gradually. Natural lipoatrophy is usually bilateral The treatment of facial lipoatrophy is not just a cosmetic therapy as noted by the Center for Medicare and Medicaid Services recent decision; if offers these patients quality of life and self-image enhancement which may also reduce depressive symptoms often associated with the stigmatism of facial fat loss